REDCapData will be collected via a secure online system run by University of Edinburgh using REDCap software, used under licence from Vanderbilt University (Nashville, Tennessee, USA; Project REDCap). REDCap is used in by 2683 active institutional partners in 117 countries around the world to securely gather research data. This system is designed specifically around US Health Insurance Portability and Accountability Act (HIPAA) security guidelines.